Admira 80mg Tablet

Uses of Admira 80mg Tablet

• Treats Type II Diabetes Mellitus in adults

How does Admira 80mg Tablet work?

Admira 80mg Tablet is highly effective in regulating blood sugar levels. The presence of gliclazide triggers the pancreas to release additional insulin, facilitating the breakdown of circulating sugars (glucose) present in the bloodstream. Moreover, it enhances the body's responsiveness to insulin, optimizing the utilization of circulating blood glucose and subsequently resulting in a reduction of blood glucose levels.

Side Effects of Admira 80mg Tablet

• Sweating
• Changes in vision
• Decreased heartbeat
• Stomach pain
• Constipation
• Skin rash
• Dizziness
• Nausea or vomiting
• Confusion
• Weakness
• Elevated liver enzymes
• Low blood sugar levels

Quick Suggestions:

• Take Admira 80mg Tabletshortly before or with the first main meal of the day (usually breakfast). Avoid skipping meals.
• Be careful while driving or operating machinery until you know how Gliclazide affects you.
• It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol, or if you delay or miss a meal.
• Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremors,s, and anxiety.
• Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Indication

Type II Diabetes mellitus (DM) stems from elevated blood sugar levels attributed to insufficient insulin production and reduced bodily response to insulin. Enter Admira 80mg Tablet, a solution for type II Diabetes. This medication stimulates insulin secretion from the pancreas, effectively curbing blood sugar levels.

Pharmacology

Gliclazide operates through multiple mechanisms to regulate blood sugar levels. It stimulates the release of insulin from pancreatic beta-cells, curtails the liver's insulin uptake and glucose production, and augments insulin sensitivity at peripheral sites within the body. Notably, it diminishes the occurrence of micro thrombosis by partially inhibiting platelet aggregation and adhesion. Furthermore, it contributes to the restoration of fibrinolysis by increasing the activity of tissue plasminogen activator (tPA). These combined effects work to maintain blood glucose levels within a healthy range.

Dosage & Administration of Admira 80mg Tablet

For the treatment of Type 2 diabetes mellitus in adults, the initial dose of Admira 80mg Tablet is 40-80 mg daily, which can be gradually increased to a maximum of 320 mg daily if needed. Doses exceeding 160 mg daily should be split into two divided doses. If using modified-release tablets, start with 30 mg once daily and may increase in increments of 30 mg up to a maximum of 120 mg daily. The interval between dose increments should be at least 1 month. In cases of non-response, the dose may be increased after 2 weeks.

Take Admira 80mg Tablet before meals or as directed by your physician. Swallow the tablet whole with a glass of water, and do not crush or chew it. Your doctor will determine the appropriate dose and duration of therapy based on factors such as your age, body weight, and disease condition. It's important to continue taking Admira 80mg Tablet as prescribed by your doctor for the recommended duration to achieve optimal control over your blood sugar levels.

Interaction

It's essential to recognize that drug interactions can vary from person to person. Before starting any medication, it's crucial to consult your doctor to thoroughly assess potential interactions. Here are some key points about interactions related to Admira 80mg Tablet:

Interaction with Alcohol: You should avoid or limit alcohol consumption while taking Admira 80mg Tablet. Alcohol can enhance the risk of side effects like confusion, dizziness, nausea, vomiting, weakness, and fainting.

Interaction with Medicine: Admira 80mg Tabletmay interact with drugs like Miconazole, Phenylbutazone, and Chlorpromazine. It's important to discuss these potential interactions with your doctor.

Disease Interactions:

• Heart Disease: If you have heart and blood vessel problems, use Admira 80mg Tablet cautiously, as it might increase the risk of heart failure.
• Type 1 Diabetes Mellitus: Admira 80mg Tablet stimulates insulin production in the pancreas. Therefore, it is not suitable for individuals with Type 1 Insulin Dependent Diabetes, where the body cannot produce insulin, necessitating insulin injections.
• Hemolytic Anaemia/G6PD Deficiency: Admira 80mg Tablet should be used cautiously if you have hemolytic anemia or G6PD deficiency, as it may worsen your condition. Symptoms include fever, dark urine, stomach pain, fatigue, and pale skin.

Food Interactions: Specific food interactions are not mentioned.

Lab Interactions: No information is provided about lab interactions.

This list does not cover all potential drug interactions. Always consult your doctor to fully understand the possible interactions of the medications you are taking. Your doctor can provide personalized guidance based on your medical history, current medications, and specific health conditions.

Contraindications

• Allergic Reaction: If you have a known allergy to gliclazide or any other ingredients in Admira 80mg Tablet.
• Type 1 Diabetes: If you have type 1 diabetes, Admira 80mg Tablet may not be appropriate as it stimulates insulin production in the pancreas, which might not be effective in type 1 diabetes.
• Kidney or Liver Problems: If you have kidney or liver problems, these conditions can affect how your body processes the medication.
• Ketones and Sugar in Urine: If you have ketones and sugar in your urine, it might indicate a problem with diabetes control that could impact the use of Admira 80mg Tablet.
• Diabetic Pre-coma or Coma: If you are experiencing or at risk of diabetic pre-coma or coma, Admira 80mg Tablet may not be suitable in these situations.
• Diabetic Patient Undergoing Surgery or Infections: If you are a diabetic patient undergoing surgery, severe trauma, or infections, Admira 80mg Tablet might not be appropriate during these situations.
• Hereditary Disease - Porphyria: If you have the hereditary disease porphyria, the use of Admira 80mg Tablet may need careful consideration.
• Taking Miconazole: If you are taking the medication miconazole to treat fungal infections, it may interact with RAdmira 80mg Tablet.
• Breastfeeding: If you are breastfeeding, Admira 80mg Tablet may not be recommended due to potential effects on the infant.

Pregnancy & Lactation

Pregnant women should avoid using gliclazide. It should not be used by a woman who is breastfeeding.

Precautions & Warnings

• Type 1 Diabetes or Diabetic Ketoacidosis: It is not suitable for patients with type 1 diabetes or those experiencing diabetic ketoacidosis, a serious complication of diabetes.
• Allergic Reaction: If you are allergic to Admira 80mg Tablet or any of its ingredients.
• Severe Liver or Kidney Problems: If you have severe liver or kidney problems, as the medication's effects may be adversely affected.
• Severe Thyroid or Adrenal Gland Problems: If you have severe thyroid or adrenal gland problems, Admira 80mg tablet may not be appropriate.
• History of Diabetic Coma: If you have ever experienced a diabetic coma in the past.
• Lactic Acidosis Risk: Some diabetic patients taking Admira 80mg Tablet might develop lactic acidosis, a rare but serious condition involving excessive lactic acid accumulation in the blood. Proper liver and kidney function is essential to eliminate excess lactic acid. Consult your doctor before use and take it only as prescribed under medical supervision.
• Medical Supervision: Consult your doctor and take Admira 80mg Tablet only if it is prescribed and monitored by a healthcare professional.
• Optimum Effects: Admira 80mg Tablet works best when combined with healthy lifestyle changes such as weight loss, regular exercise, and a healthy diet.

Storage Conditions

• Store in a cool and dry place, below 30°C.
• Keep it away from children and pets in the original package.
• Avoid using expired medicines.