Almex 400mg | Albendazole | View Uses, Interaction | Medicine | ePharma
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Almex 400mg Tablet

Generic: Albendazole

Type: Tablet

Pack Size: 4 pcs

Almex 400mg Tablet is an anti-worm medicine containing Albendazole as its active ingredient. It is used for treating stomach or intestinal infections caused by various worms.


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Discount Price: ৳ 22.32
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Description:

Almex 400mg Tablet is an anthelmintic drug used to treat various worm infections caused by parasites. It is effective against infections such as neurocysticercosis, cystic hydatid disease, roundworms, hookworms, threadworms, whipworms, pinworms, flukes, and other parasites.

The active ingredient in Almex 400mg Tablet is Albendazole, which works by inhibiting tubulin polymerization. This disrupts the metabolism and energy supply of the parasite, leading to its immobilization and eventual death.

Here are some important points to consider when taking Almex 400mg Tablet:

  • Take Almex 400mg Tablet exactly as prescribed by your doctor. The duration of treatment will depend on your specific medical condition. Follow your doctor's instructions carefully.
  • Some common side effects of Almex 400mg Tablet include stomach pain, nausea, vomiting, headache, and dizziness. These side effects are generally temporary and do not require medical attention. However, if these side effects persist, it is advisable to consult your doctor.
  • Almex 400mg Tablet may increase the infection risk. It is important to maintain proper hygiene and avoid close contact with individuals who have infections, flu, or colds.
  • While taking Almex 400mg Tablet, be cautious if you notice unusual bleeding or bruising, as it may indicate a potential effect on blood clotting. Consult your doctor if you experience such symptoms.
  • Before taking Almex 400mg Tablet, inform your doctor if you have any liver or kidney problems. This information is important for your doctor to determine the appropriate dosage and monitor your health during the treatment.
  • Almex 400mg Tablet is not recommended for use in pregnant or breastfeeding women due to an increased risk of side effects. Do not breastfeed during and for a minimum of 5 days after treatment with Almex 400mg Tablet. If you are pregnant or breastfeeding, discuss alternative treatment options with your doctor.
  • Both men and women taking Almex 400mg Tablet should take appropriate precautions to prevent pregnancy. This can be done by using condoms or contraceptive pills while taking the medication and for 3-6 months after discontinuing the therapy. It is important to discuss the appropriate contraceptive methods with your doctor.
  • Please note that Almex 400mg Tablet should not be given to children below 2 years of age. The safety and efficacy of the medication in this age group have not been established.
  • Keep your doctor informed about your health condition and any other medications you may be taking. This helps to ensure that there are no potential interactions or adverse effects.

Safety Advices


Alcohol
UNSAFE

Drinking alcohol, along with this medicine, may increase the risk of liver problems. It is advised to limit the consumption of alcohol during the treatment.


Pregnancy
UNSAFE

Almex 400mg Tablet is not recommended for pregnant women. Inform your doctor if you are pregnant or planning to become pregnant. Women of childbearing potential should use contraception during Almex 400mg Tablet therapy and for 6 months after stopping it.


Breastfeeding
CAUTION

It is unknown if Albendazole passes into breast milk. Caution is advised when Albendazole is used while breastfeeding.


Driving
CAUTION

Do not drive or operate any heavy tools or machines if you experience dizziness after taking Almex 400mg Tablet


Kidney
CAUTION

Almex 400mg Tablet should be used with caution in patients with kidney diseases. Therefore, consult your doctor before taking it.


Liver
CAUTION

Almex 400mg Tablet should be used with caution in patients with liver diseases. Therefore, consult your doctor before taking it.

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Uses of Almex 400mg Tablet
  • Treatment of Parasitic worm infections
How does Almex 400mg Tablet work/

Almex 400mg Tablet works by decreasing the energy sources of the parasite. This medicine reduces the sugar and nutrient uptake of the parasite, making it weaker, and eventually killing it.

Side Effects of Almex 400mg Tablet
  • Headache
  • Dizziness
  • Nausea and Vomiting
  • Abdominal pain
  • Hair loss or thinning of the hair
  • Fever
  • Low blood cell count
  • Skin rash and itching
  • Diarrhea
Quick Suggestions:
  • Pregnancy: Do not take Albendazole if you are pregnant, as it can be harmful to the unborn baby. Use effective birth control measures during treatment with Albendazole to prevent pregnancy.
  • Blood counts and liver function: Your doctor may monitor your blood cell count and liver function before starting Albendazole and regularly throughout your treatment. It helps ensure the medication is not causing any adverse effects on these parameters.
  • Infection prevention: Avoid close contact with people who are sick or have infections. If you develop signs of infection, inform your doctor promptly.
  • Completing the course: Take Albendazole as prescribed by your doctor and complete the full course, even if you start to feel better. Skipping doses or stopping the medication early may increase the risk of a recurring or persistent infection.
  • Hand hygiene: Wash your hands thoroughly with soap and water, especially after using the toilet and before eating.
  • Food safety: Avoid eating raw or undercooked fish and meat. Cook meat thoroughly before consuming. Wash all fruits and vegetables properly before eating. Reheat or wash food that has been kept for a long time. Avoid contact with soil that may be contaminated with feces. Avoid consuming foods kept open in markets, as they can be contaminated.
  • Water safety: Drink boiled and purified water to minimize the risk of infection.
  • Monitoring during treatment: Regularly monitor your blood cell count and liver function as advised by your doctor while taking Almex 400mg Tablet.
  • Infection risk: Almex 400mg Tablet may increase the chances of getting an infection. Practice good hygiene and try to avoid close contact with individuals who have infections, flu, or colds.
  • Unusual bleeding or bruising: If you notice any unusual bleeding or bruising, consult your doctor, as Albendazole may increase the tendency to bleed or bruise easily.
  • Viral infections: Remember that Albendazole will not treat viral infections such as the flu or the common cold.
Indication

Albendazole is used in the treatment of single or mixed intestinal infections caused by Enterobius vermicularis (Pinworm, Threadworm), Trichuris trichiura (Whipworm), Ascaris lumbricoides (Roundworm), Ancylostoma duodenale & Necator americanus (Hookworm), Taenia solium & Taenia saginata (Tapeworm), Strongyloides stercoralis. Albendazole is indicated in giardiasis in children over 2 years of age. Albendazole in higher doses is indicated for the treatment of hydatid disease.

Pharmacology

Almex 400 is a broad-spectrum anthelmintic medication that contains the active ingredient Albendazole. Albendazole exhibits various activities against parasites, including insecticidal, ovicidal, and larvicidal effects.

The primary mechanism of action of Albendazole as an anthelmintic is believed to involve the inhibition of glucose uptake by susceptible worms. This leads to a depletion of energy levels within the parasite, ultimately resulting in its immobilization and death. This effect is thought to occur through the binding of albendazole and its metabolites to parasite tubulin, which inhibits tubulin polymerization. It's important to note that albendazole also binds to human tubulin.

Albendazole is extensively metabolized, primarily in the liver. It is poorly absorbed from the gastrointestinal tract but undergoes rapid and extensive first-pass metabolism. One of the major metabolites of Albendazole is albendazole sulfoxide, which retains its anthelmintic activity. The half-life of albendazole sulfoxide in plasma is approximately 8.5 hours. Albendazole and its metabolites are excreted in the urine, along with other metabolites.

It's worth mentioning that the information provided here is a general overview and should not replace the specific instructions and advice given by your healthcare provider. If you have any concerns or questions about Almex 400 or its usage, it is recommended to consult with your doctor or pharmacist for personalized guidance.

Dosage & Administration of Almex 400mg Tablet

The recommended dosages of Albendazole for various parasitic infections are as follows:

For Adults & Children over 2 years:

  • Enterobius vermicularis, Trichuris trichiura, Ascaris lumbricoides, Ancylostoma duodenale, and Necator americanus: A single dose of 400 mg (1 tablet or 10 ml suspension).
  • Strongyloidiasis or taeniasis: 400 mg (1 tablet or 10 ml suspension) daily for 3 consecutive days. If not cured after three weeks, a second course of treatment may be necessary.

For Children of 1-2 years:

  • A single dose of 200 mg (5 ml suspension).

For Children under 1 year:

  • Albendazole is not recommended.

In Hydatid disease (Echinococcosis):

  • For patients weighing over 60 kg: 400 mg (1 tablet) twice daily with meals for 28 days.
  • For patients weighing less than 60 kg: A daily dose of 15 mg/kg body weight (up to a maximum total daily dose of 800 mg) in two divided doses.

For giardiasis:

  • 400 mg (1 tablet or 10 ml suspension) once daily for five days.

When taking Almex 400mg Tablet, follow your physician's instructions. Swallow the tablet with a glass of water, without crushing or chewing it. If you are using a chewable tablet, chew it thoroughly before swallowing.

It's essential to complete the full course of therapy as prescribed by your doctor, even if your symptoms improve. Stopping the medication early may result in incomplete treatment and inadequate control of the infection.

Remember to consult your healthcare provider for personalized advice and dosage instructions based on your age, body weight, and the severity of the infection.

Interaction

Almex 400mg Tablet may interact with the following medications:

  • Dexamethasone: Dexamethasone can increase the plasma levels of albendazole metabolites. Adjustments in the dosage may be required under a doctor's supervision when using these medications together.
  • Cimetidine: Cimetidine may interact with albendazole, although the specific nature of the interaction is not mentioned. It is advisable to inform your doctor if you are taking cimetidine along with Almex 400mg Tablet.
  • Theophylline: Theophylline may interact with albendazole, although the specific nature of the interaction is not mentioned. It is advisable to inform your doctor if you are taking theophylline along with Almex 400mg Tablet.
  • Praziquantel: Praziquantel may increase the plasma concentrations of albendazole by 50%. Adjustments in the dosage may be necessary when using these medications together.

Regarding drug-food interactions, no specific interactions have been established for Almex 400mg Tablet.

Almex 400mg Tablet may also have interactions with certain diseases:

  • Myelosuppression (bone marrow suppression): Inform your doctor if you have myelosuppression before taking Almex 400mg Tablet.
  • Hepatobiliary dysfunction (liver and biliary disease): Inform your doctor if you have any liver or biliary disease before taking Almex 400mg Tablet.
  • Neurological disorder: Inform your doctor if you have a neurological disorder before taking Almex 400mg Tablet.
  • Kidney dysfunction: Inform your doctor if you have kidney dysfunction before taking Almex 400mg Tablet.

It is important to discuss your medical history and any ongoing treatments with your doctor before starting Almex 400mg Tablets to ensure their safe and effective use. Your doctor will be able to provide personalized advice and adjust the dosage or prescribe alternative medications if needed.

Contraindications
  • If you are allergic to the Benzimidazole class of medicines like Mebendazole or any other components of Almex 400mg Tablet.
  • Neonates: Albendazole is not normally used in neonates.
  • Children: Reduction of the dose from 400 mg to 200 mg may be indicated in children weighing less than 10 kg but there are no grounds for a general reduction in dosage to children.
  • Pregnant woman: Albendazole should not be given during pregnancy or to women thought to be pregnant. No information is available on placental transfer.
  • Concurrent disease: There is no evidence to suggest that the dose should be altered in renal, hepatic, or cardiac failure.
Pregnancy & Lactation

Albendazole is classified by the U.S. Food and Drug Administration (FDA) as Pregnancy Category C. This means that it should be used during pregnancy or lactation only if the potential benefits to the mother outweigh the potential risks to the fetus or nursing infant.

Pregnancy Category C indicates that studies in animals have shown adverse effects on the fetus, but there are no adequate and well-controlled studies in pregnant women. Therefore, the use of albendazole in pregnant women should be carefully considered, and the potential risks and benefits should be discussed with a healthcare professional.

Similarly, caution should be exercised when using albendazole during breastfeeding, as it may pass into breast milk. The decision to use albendazole while breastfeeding should be made in consultation with a healthcare provider, considering the importance of the medication for the mother's health and the potential risks to the nursing infant.

It is important to follow the guidance of your healthcare provider and discuss any concerns or questions you may have regarding the use of albendazole during pregnancy or lactation. They will be able to provide you with the most appropriate advice based on your individual circumstances.

Precautions & Warnings
  • Do not take Almex 400mg Tablet if you are allergic to any of its ingredients.
  • Almex 400mg Tablet may cause bone marrow suppression, aplastic anemia, and agranulocytosis. These are serious conditions that affect blood cell production. Regular monitoring of blood cell counts is advised during treatment.
  • Inform your doctor if you have a history of liver disease or if you are scheduled for any surgery, including dental surgery.
  • Seek immediate medical attention if you experience seizures, vomiting, headache, extreme tiredness, or behavior changes while taking Almex 400mg Tablet.
  • Almex 400mg Tabletmay increase the risk of infections. Practice good hygiene and avoid close contact with people who have infections, the flu, or colds.
  • Consult your doctor if you notice unusual bleeding or bruising, as Almex 400mg Tablets may affect blood clotting.
  • Almex 400mg Tablet should not be taken during pregnancy or if you are planning to become pregnant, as it may cause harm to the fetus. It is also not recommended during breastfeeding. Consult your doctor for appropriate alternatives.
  • Almex 400mg Tablet may cause dizziness, so use caution when driving or operating machinery.
  • Almex 400mg Tablet can be prescribed for children, but it should be done under the supervision of a doctor.
Storage Conditions
  • It should be kept in a dry place at a temperature below 30°C
  • Please protect it from light
  • Keep it out of reach of children
Frequently Asked Questions (FAQ)

Albendazole tablet works as an antiparasitic medication and is generally used in the prevention and treatment of parasitic infections caused by tapeworms, pinworms and hookworms. It contains Albendazole as a working ingredient. This tablet works by keeping the worms from absorbing sugar (glucose), thereby depleting their energy level. It causes the worms to die and treats your infection.

The time taken for Almex 400mg Tablet to show its effect is 2-5 hours of its intake.

Almex 400mg Tablet may remain active in your body for an approximate duration of 2 to 3 days.

Yes

Albendazole is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

No, Albendazole is not an over the counter (OTC) product. It is a prescription medicine which means it can be bought with a valid prescription by a doctor only.

If you forget a dose of Albendazole, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

Albendazole should not be used in pregnancy or if you are planning a pregnancy Women of childbearing age are advised to take this medicine during their first week of menstruation or after a negative pregnancy test Women should also take measures not to have a positive pregnancy test until one month after stopping this medication

You should take Almex 400mg Tablet exactly as told by the doctor. It can be taken with or without food, preferably at a fixed time.
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ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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