Traxyl 500mg 10pcs

✔️ Tranexamic Acid 500mg Capsule

In Medicine:

• Prophylaxis and treatment of hemoptysis, gastrointestinal bleeding, hemorrhagic conditions in leukemia, cirrhosis, hemophilia, thrombocytopenic purpura, thrombolytic therapy complications, and transfusion-related accidents.

In Surgery:

• Prevention and control of bleeding during surgeries, especially in pulmonary, cardiovascular, abdominal, and urological procedures. Useful in post-operative bleeding and traumatic shock.

In Urology:

• Prophylaxis and treatment of bleeding during surgeries of the prostate, bladder, and kidneys. Effective for hematuria.

In Obstetrics:

• Prevention and treatment of post-partum and puerperium hemorrhages, abnormal uterine bleeding (idiopathic or IUD-induced), and hemorrhages due to abruptio placentae or premature placental detachment. Used during cervical conization.

In Otorhinolaryngology:

• Prophylaxis and treatment of bleeding during tonsillectomies, specialized surgeries, and epistaxis.

In Stomatology:

• Prevention and treatment of bleeding during maxillofacial surgeries and tooth extractions.

In Oncology (supportive therapy):

• Helps form a fibrin capsule around ovarian tumors to limit their growth. Reduces ascites caused by carcinoma and minimizes bleeding during cancer surgeries.

✔️ Dosage & Administration of Traxyl 500

Adults:

• General dose: 500-1000 mg taken three times daily.
• For prophylaxis: 0.5-1 g orally or 500 mg via intravenous or intramuscular routes daily.
• For bleeding management: 1-3 g orally in divided doses. For urgent cases, start with a 500 mg intravenous injection, followed by oral doses as needed.

Children:

• Prophylaxis: 5-10 mg/kg daily, divided into multiple doses.
• Treatment: Oral doses are increased to 10-20 mg/kg. For intravenous or intramuscular use, begin with 10 mg/kg (0.5 mL per 5 kg) administered slowly. Diluted ampoules may also be given orally for convenience.

Elderly:

• No dosage adjustments are required unless renal function is impaired.

✔️ Side Effects

• Common: Fatigue, nasal congestion, skin redness, itching, and conjunctival irritation.
• Gastrointestinal: Nausea, diarrhea, and heartburn.
• Rare: Postural hypotension and hypersensitivity reactions requiring discontinuation.

✔️ Interaction

• Antibiotics: Incompatible with solutions containing penicillins (e.g., benzylpenicillin).
• Thrombolytics: Streptokinase and urokinase antagonize Tranexamic Acid’s effects.
• Oral Contraceptives: Concurrent use may increase the risk of thrombosis.
• Blood Transfusions: Avoid mixing Tranexamic Acid directly with whole blood.

✔️ Contraindications

• Hypersensitivity to Tranexamic Acid.
• Thromboembolic disorders, arterial and venous thrombosis, endocavitary bleeding, or severe renal failure.

✔️ Pregnancy & Lactation

• Tranexamic Acid should be avoided during pregnancy due to unknown transplacental effects.
• A minimal amount of the drug is excreted into breast milk, making an antifibrinolytic effect on the infant unlikely.

✔️ Precautions & Warnings

• Use only in cases of hyperfibrinolysis. Begin prophylactic treatment 24 hours before surgery and continue for 3-4 days post-surgery.
• Continue therapy for 24 hours after hemorrhagic symptoms resolve.
• Reduce doses in hematuria to prevent clot formation in the urinary tract.
• Avoid use in severe renal failure or anuric syndromes; use cautiously in patients with moderate renal dysfunction, heart disease, or liver disorders.

✔️ Storage Conditions

Store in a dry place at 15-30°C, away from light. Keep out of reach of children.