Cloram 0.50% Sterile Eye/Ear Drops

Composition:

Chloramphenicol

Uses of Cloram 0.50% Sterile Eye/Ear Drops

• Bacterial eye infections

How does Cloram 0.50% Sterile Eye/Ear Drops work?

Cloram 0.50% Sterile Eye/Ear Drops works by preventing the synthesis of essential proteins that are necessary for vital bacterial functions. Thereby, acts against the bacteria and helps in treating and preventing the spread of infections.

Side Effects of Cloram 0.50% Sterile Eye/Ear Drops

Blood dyscrasias may develop after extended ophthalmic usage, including granulocytopenia, thrombocytopenia, and mild anemia.

Quick Suggestions:

• Do not skip any doses and finish the full course of treatment even if you feel better.
• Do not touch the tip to any surface, or to your eye, to avoid contamination.
• Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
• You should continue using the medicine for 48 hours after your symptoms have cleared up. However, do not use it for longer than five days without consulting your doctor.
• It may cause short-term blurring of vision when first used. Use caution before driving or using machines.
• Talk to your doctor if your symptoms haven't started to improve within two days of starting treatment if they get worse during treatment, or if you get another eye infection.
• Do not wear contact lenses until your infection clears up.
• Throw away any medicine left at the end of the 5-day course.

Indications of Cloram 0.50% Sterile Eye/Ear Drops

Chloramphenicol, the powerhouse in Cloram 10 ml, is your go-to solution for bacterial infections of the conjunctiva and cornea caused by chloramphenicol-resistant organisms. Targeting bacteria like Staphylococcus aureus, Streptococcus pneumoniae, E. coli, H. influenzae, Klebsiella/Enterobacter spp, Moraxella lacunata, and Neisseria species, ensures effective infection control.

Pharmacology

Chloramphenicol, a broad-spectrum bacteriostatic antibiotic, takes charge by disrupting the transfer of activated amino acids from soluble RNA to ribosomes. This interference proves detrimental to bacterial protein production, ensuring a robust defense mechanism.

Dosage & Administration of Cloram 0.50% Sterile Eye/Ear Drops

• Adult and Children: Instill 1 or 2 drops in the conjunctival sac 4-6 times per day for the initial 72 hours.
• Continue every 4 hours thereafter.
• Treatment duration: Approximately 7 days, not exceeding 3 weeks without re-evaluation by a physician.

Interaction

Recognition of potential persistent fungal infections is essential after chronic corticosteroid use. Caution is advised, as multiple dosage containers have been linked to bacterial keratitis, particularly in cases of ocular epithelial surface disturbance.

Contraindications

Individuals with a history of hypersensitivity to chloramphenicol or any components of the preparation should steer clear.

Pregnancy & Lactation

Safe use during pregnancy or lactation is undetermined. Employ only when deemed necessary by healthcare professionals.

Precautions & Warnings

• Avoid use for mild infections.
• Exercise caution with repeated or prolonged treatments.
• Blood dyscrasias may emerge after extended ophthalmic use.

Storage Conditions

• Store in a cool place (between 2°C-8°C).
• Keep it dry and protected from light.
• Out of reach of children.
• Do not touch the dropper tip to surfaces.
• Discard after 30 days of the first opening.