Aristoderm Cream

Uses of Aristoderm Cream

Fungal and bacterial skin infections, psoriasis, eczema, ringworm, athlete's foot, and jock itch.

How does Aristoderm Cream work?

Betamethasone + Clotrimazole + Gentamicin is a combination of three medicines: Betamethasone, Clotrimazole, and Gentamicin. Betamethasone is a steroid that blocks the production of certain chemical messengers (prostaglandins) that make the affected area red, swollen, and itchy. Clotrimazole is an antifungal which stops the growth of fungi while Gentamicin is an antibiotic that stops the growth of bacteria. Together, they treat your infection effectively.

Side Effects of Aristoderm Cream

• Burning
• Irritation
• Itching
• Redness

Quick Suggestions:

• Betamethasone + Clotrimazole + Gentamicin helps treat skin infections.
• It is for use on the skin only. Do not use it in your eyes, mouth, or vagina. Rinse with cold water if you accidentally get it in these areas.
• Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
• If you think the area of skin you are treating has become more irritated, you should stop using Betamethasone + Clotrimazole + Gentamicin and consult your doctor.
• Don't use this medicine more often or for longer than advised by your doctor. Inform your doctor if the treated skin area does not improve after 1 week of treatment.

Indication of Aristoderm Cream

Aristoderm Cream is indicated for the treatment of oozing eczema, generalized eczema, atopic dermatitis, seborrheic dermatitis, contact dermatitis as well as some forms of psoriasis, impetigo, tinea pedis, tinea cruris, and tinea corporis etc.

Pharmacology

• Aristoderm Cream combines three active ingredients: Betamethasone Dipropionate, Clotrimazole, and Gentamicin Sulfate.
• Betamethasone Dipropionate: A synthetic fluorinated corticosteroid that has anti-inflammatory, anti-pruritic (anti-itch), and vasoconstrictive properties.
• Clotrimazole: A broad-spectrum antifungal agent that affects the fungal cell membrane, causing leakage of its contents.
• Gentamicin Sulfate: A bactericidal antibiotic effective against various gram-negative and gram-positive bacteria.
• Betamethasone Dipropionate: Provides rapid and sustained anti-inflammatory effects, commonly used in inflammatory dermatoses responsive to topical corticosteroids.
• Gentamicin Sulfate: Exhibits bactericidal activity against a wide range of pathogenic bacteria, both gram-negative and gram-positive.
• Clotrimazole: Apart from its antifungal activity, it also exhibits activity against Trichomonas (a parasite), Staphylococci, Streptococci, and Bacteroides.
• Gentriderm cream is indicated for the treatment of inflammatory and allergic dermatological conditions that are threatened or complicated by bacterial and/or common fungal infections.
• It provides a combination of anti-inflammatory, antipruritic, bactericidal, and fungicidal actions.

Dosage & Administration of Aristoderm Cream

Frequency of Application:

• Apply the cream to the affected skin areas two times daily.
• It's important to follow the prescribed dosage and frequency as directed by your healthcare provider.

Quantity Limit:

• Limit the total weekly application of the cream to less than 45 grams.
• This ensures that you are using an appropriate amount of the medication.

Duration of Therapy:

• The duration of therapy can vary depending on the extent and location of the disease, as well as individual patient response.
• If clinical improvement is not achieved within 3-4 weeks of treatment, it is advisable to review the diagnosis with your healthcare provider.

Application Method:

• Before applying the cream, ensure that your hands are clean and dry.
• Apply a thin layer of the cream to the affected areas of the skin.
• You can use clean cotton wool or a gauze swab to apply the cream if preferred.
• Gently rub the cream into the skin until it is absorbed.

Hand Hygiene:

• It is recommended to wash your hands before and after applying the cream, unless the treatment is specifically for the hands.
• This helps maintain cleanliness and prevents the spread of the medication to unintended areas.

Avoid Contact with Eyes, Nose, and Mouth:

• The Aristoderm Cream is for external use only.
• If the cream accidentally comes into contact with your eyes, nose, or mouth, rinse thoroughly with cold water.

Interaction

Drug-Drug Interaction:

• It is important to inform your doctor about all the medicines you are using, including topical products, before starting Aristoderm Cream.
• This helps your doctor to assess potential interactions between BETAMETHASONE+CLOTRIMAZOLE+GENTAMICIN and other medications you are taking.

Drug-Food Interaction:

• No specific interactions between Aristoderm Cream and food have been found or established.
• This suggests that the medication can generally be used without dietary restrictions.

Drug-Disease Interaction:

• If you have a medical history of allergic reactions to medicines, it is important to inform your doctor before using Aristoderm Cream.
• Additionally, if you have active skin infections, it is recommended to brief your doctor about this before using the medication.
• These precautions help ensure the safe and appropriate use of Aristoderm Cream based on your medical history and condition.

Contraindications

This Cream is contraindicated in those patients with a history of sensitivity reactions to any of its components.

Pregnancy & Lactation

Indeed, the use of topical corticosteroids during pregnancy should be carefully considered. While there is limited evidence on the safety of these medications in pregnant women, they may be prescribed if the potential benefit to the mother outweighs the potential risk to the fetus. The decision should be made in consultation with a healthcare provider, taking into account the specific circumstances and the severity of the condition being treated.

Similarly, when it comes to breastfeeding, the value of the drug to the lactating mother should be weighed against the potential risk to the nursing infant. It is important to discuss this with a healthcare provider to make an informed decision about continuing nursing or temporarily discontinuing it while using the medication.

Ultimately, the safety and appropriateness of using topical corticosteroids during pregnancy and lactation depend on various factors, and healthcare providers are best equipped to provide individualized guidance based on the specific situation.

Precautions & Warnings

Similar Effect to Systemic Steroid Therapy:

• Aristoderm Cream may have a similar effect to systemic steroid therapy when used in large amounts or for long-term therapy using the occlusive dressing technique (ODT).
• This can lead to local adverse effects such as skin atrophy (thinning of the skin) and facial erythema (redness of the face).
• Discontinue the use of Aristoderm Cream if these reactions occur.

Hypersensitivity Reactions:

• Hypersensitivity reactions, including itching, flare, vesicles (small fluid-filled sacs), and urticaria (hives), may occur.
• Discontinue the use of Aristoderm Cream if these manifestations of hypersensitivity occur.

Overdosage and Prolonged Therapy:

• Aristoderm Cream should not be used in overdosage or for prolonged therapy using the occlusive dressing technique.
• It is important to adhere to the prescribed dosage and duration of treatment.

Eye Use:

• Aristoderm Cream should not be used in the eyes. It is intended for external use only.

Monitoring and Discontinuation:

• If there is no improvement or if the condition worsens, discontinue the use of Aristoderm Cream.
• Resume treatment as soon as possible once improvements are observed.

Pregnancy and Lactation:

• The use of Aristoderm Cream during pregnancy and lactation should be discussed with a healthcare provider, considering the potential risks and benefits.

Combination with Corticosteroid Medicines:

• Aristoderm Cream should not be combined with other corticosteroid-containing medicines.

Specific Application Instructions:

• Do not apply Aristoderm Cream on the face or near the eyes.
• Avoid using it for lengthy periods of time, on large areas, beneath an occlusive dressing, on open wounds, wounded areas, outside genital areas, or in skin folds.

Storage Conditions

Store below 25° C and dry place protected from light.